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Duke Fang SBSDI Retinal OCT Dataset

Human and human-derived paired retinal OCT images used to study sparse acquisition, denoising, interpolation, and reconstruction in healthy and non-neovascular AMD eyes.

Duke RPE-Drusen Complex OCT Dataset

OCT data from 384 subjects, including 269 with AMD and 115 normal subjects, with 38,400 B-scans and derived total retina and RPE-drusen complex thickness measurements.

Duke Srinivasan Retinal OCT Dataset

Forty-five retinal OCT volumes acquired with a Spectralis system: 15 dry AMD, 15 diabetic macular edema, and 15 normal volumes. The official Duke release provides the study data.

EED-Astig Pediatric External-Eye Dataset

Pediatric external-eye photographs with gaze-view annotations, corneal masks, eyelid/eyelash-line keypoints, and clinical tabular parameters for astigmatism-related research.

FIRE: Fundus Image Registration Dataset

129 fundus images from 39 patients forming 134 registration pairs with anatomical ground-truth control points. Only public registration benchmark for ophthalmology.

iChallenge OCT Datasets (HDMILab / OMIA Workshops)

OCT challenge datasets from HDMILab covering retinal layer segmentation and fluid detection tasks from MICCAI/OMIA workshops. Includes sub-challenges such as AMD/CSC/DR classification and retinal laye

LPW Labelled Pupils in the Wild

High-speed head-mounted eye-region videos with pupil-center annotations under varied indoor, outdoor, eyewear, and lighting conditions.

mBRSET: Mobile Brazilian Retinal Dataset

5,164 fundus images from 1,291 patients captured with the Phelcom Eyer handheld smartphone-based fundus camera. Labels for DR grading + clinical/demographic prediction.

MESSIDOR-2

1748 fundus images with DR grading (0-3 Retinopathy Grade) and macular edema risk (0-2).

ND-IRIS-0405 Iris Image Dataset

Longitudinal near-infrared iris images with subject, eye, age, sex, and ethnicity metadata used in ICE iris-recognition evaluations.

Rasti OCT Dataset (Noor Eye Hospital, Tehran)

148 Heidelberg Spectralis SD-OCT volumes (~4,254 B-scans) for 3-class volume-level classification: Normal (50 volumes), AMD (48 volumes), DME (50 volumes). Variable B-scans per volume: 19, 25, 31, or

RETOUCH: RETinal OCT Fluid Challenge

112 OCT volumes from three vendors (Cirrus / Spectralis / Topcon) with pixel-level segmentation of intraretinal fluid (IRF), subretinal fluid (SRF), and pigment epithelium detachment (PED).

THOCT1800 Retinal OCT Dataset

A collection of 1,800 preprocessed retinal OCT B-scans, with 600 images each for AMD, diabetic macular edema, and normal retina.

Tsukazaki Hospital UWF Fundus Dataset

13,047 ultra-widefield fundus photographs (Optos, 200° FOV) from Tsukazaki Hospital, annotated with 8 binary disease labels: AO, AMD, DR, Glaucoma, MH, RD, RP, RVO. Associated with Scientific Data 202

UWF DR Reasoning Dataset

Ultra-widefield fundus photographs for diabetic retinopathy grading (5-level ICDR scale). Released alongside the Reasoning-Enhanced VLM paper for interpretable UWF DR detection. Related to the UWF4DR