Functional OCT Retinal Response Dataset

Repeated light/dark SD-OCT acquisitions and retinal reflectivity profiles from healthy, neuromyelitis-optica, and Alzheimer groups.

At a glance

Field	Value
Short name	dryad_functional_oct_alzheimer
Full name	Functional OCT Retinal Response Dataset
Publication date	2019-11-18
Date basis	Initial dataset release
Publication date precision	day
Publication date evidence	datadryad.org/api
Publication date source field	versions[versionNumber=4].publicationDate (earliest public version)
Publication date reviewed	2026-09-11
Date notes	-
Primary category	oct
Resource role	current_dataset
Dataset family	dryad_functional_oct_alzheimer
Contained modalities	oct
Tasks	classification, registration, regression
Primary reported quantity	40 participants
Classes	Not reported (Not reported)
Splits	all
Size	0.843520297 GB
Source-stated terms	CC0 1.0
Normalized terms	cc0
Descriptive screening label	Standard label without an explicit NC clause; not a permission finding
Terms scope	dataset_files
Access friction	self_service_authenticated
Route backend	Dryad
Availability	available (checked 2026-07-21)
Acquisition support	end_to_end_tested
Legacy sample-loader status	Metadata and access only

Reported quantities

Role	Count	Unit	Scope	Basis	Evidence
Primary	40	participants	Unique participant identifiers across the two deposited profile tables in Dryad version 6 The Experiment 2 table has four participants, three of whom also occur in the Experiments 1, 3, and 4 table.	current_deposit_table	https://doi.org/10.5061/dryad.msbcc2ftc
Additional	1,370	rows	Processed retinal-reflectivity profile rows across the two deposited tables	current_deposit_table	https://doi.org/10.5061/dryad.msbcc2ftc
Additional	432	images	ANALYZE-format .img objects in the Dryad version 6 archive This file count includes raw, manually marked, flattened, and spatially normalized representations and is not an independent acquisition count.	current_deposit_file_listing	https://doi.org/10.5061/dryad.msbcc2ftc
Additional	1	deposited_files	RAR archive in Dryad version 6	current_deposit_file_listing	https://doi.org/10.5061/dryad.msbcc2ftc
Additional	8	group_enrollments	Healthy young-adult experiment	official_source_description	https://doi.org/10.5061/dryad.msbcc2ftc
Additional	3	group_enrollments	Aquaporin-4 antibody experiment	official_source_description	https://doi.org/10.5061/dryad.msbcc2ftc
Additional	14	group_enrollments	Early-onset Alzheimer group	official_source_description	https://doi.org/10.5061/dryad.msbcc2ftc
Additional	14	group_enrollments	Age-matched control group Group counts are not summed because cross-experiment overlap was not resolved.	official_source_description	https://doi.org/10.5061/dryad.msbcc2ftc

Counts retain their source-reported units. Additional rows can describe components, paired items, or derivative copies and are not automatically added to the primary quantity.

Notes

The current version contains 40 unique participant identifiers across four experiments, including overlapping experiment groups. Dryad file downloads require a user-supplied API token; EyeDataHub can also obtain a fresh token from locally configured Dryad client credentials.

Access information and download

CLI

# Read-only preflight
eyehub download dryad_functional_oct_alzheimer --data-dir ./data --dry-run --json

# Download, only when preflight reports supported behavior
eyehub download dryad_functional_oct_alzheimer --data-dir ./data

Python

from eyedatahub.acquisition import preflight_dataset
from eyedatahub.datasets.registry import REGISTRY

ds = REGISTRY.get_dataset('dryad_functional_oct_alzheimer')
print(preflight_dataset(ds, './data'))  # no download

Upstream page: https://doi.org/10.5061/dryad.msbcc2ftc

Source-term evidence: https://doi.org/10.5061/dryad.msbcc2ftc

Loader status

This catalog record provides metadata and access instructions, but it does not yet include a standard DatasetSample loader. Inspect the source file structure or contribute a loader before using it in a training pipeline.

Citation

BibTeX

@misc{dryad_functional_oct_alzheimer,
  title  = { Functional OCT Retinal Response Dataset },
  note   = { Bissig D, Zhou C, Le V, Bernard J. A practical approach to functional optical coherence tomography shows abnormal retinal responses in Alzheimer's disease. Dryad. 2020. doi:10.5061/dryad.msbcc2ftc },
  year   = { 2020 },
  url    = { https://doi.org/10.5061/dryad.msbcc2ftc },
}

Plain text

Bissig D, Zhou C, Le V, Bernard J. A practical approach to functional optical coherence tomography shows abnormal retinal responses in Alzheimer's disease. Dryad. 2020. doi:10.5061/dryad.msbcc2ftc

Source-stated terms

• Raw source string: CC0 1.0
• Normalized category: cc0
• Apparent scope: dataset_files
• Descriptive screening label: Standard label without an explicit NC clause; not a permission finding

⚠️ Source-stated terms, scope, and normalized labels are curation metadata, not legal advice or a permission finding. Review the current official source before transfer or reuse.

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